diff --git a/src/test/validation_block_tests.cpp b/src/test/validation_block_tests.cpp
index 5dee034b2..ad3778ccc 100644
--- a/src/test/validation_block_tests.cpp
+++ b/src/test/validation_block_tests.cpp
@@ -10,6 +10,7 @@
 #include <miner.h>
 #include <pow.h>
 #include <random.h>
+#include <script/standard.h>
 #include <test/setup_common.h>
 #include <validation.h>
 #include <validationinterface.h>
@@ -18,6 +19,8 @@ struct RegtestingSetup : public TestingSetup {
     RegtestingSetup() : TestingSetup(CBaseChainParams::REGTEST) {}
 };
 
+static const std::vector<unsigned char> V_OP_TRUE{OP_TRUE};
+
 BOOST_FIXTURE_TEST_SUITE(validation_block_tests, RegtestingSetup)
 
 struct TestSubscriber : public CValidationInterface {
@@ -59,8 +62,21 @@ std::shared_ptr<CBlock> Block(const uint256& prev_hash)
     pblock->hashPrevBlock = prev_hash;
     pblock->nTime = ++time;
 
+    pubKey.clear();
+    {
+        WitnessV0ScriptHash witness_program;
+        CSHA256().Write(&V_OP_TRUE[0], V_OP_TRUE.size()).Finalize(witness_program.begin());
+        pubKey << OP_0 << ToByteVector(witness_program);
+    }
+
+    // Make the coinbase transaction with two outputs:
+    // One zero-value one that has a unique pubkey to make sure that blocks at the same height can have a different hash
+    // Another one that has the coinbase reward in a P2WSH with OP_TRUE as witness program to make it easy to spend
     CMutableTransaction txCoinbase(*pblock->vtx[0]);
-    txCoinbase.vout.resize(1);
+    txCoinbase.vout.resize(2);
+    txCoinbase.vout[1].scriptPubKey = pubKey;
+    txCoinbase.vout[1].nValue = txCoinbase.vout[0].nValue;
+    txCoinbase.vout[0].nValue = 0;
     txCoinbase.vin[0].scriptWitness.SetNull();
     pblock->vtx[0] = MakeTransactionRef(std::move(txCoinbase));
 
@@ -69,6 +85,9 @@ std::shared_ptr<CBlock> Block(const uint256& prev_hash)
 
 std::shared_ptr<CBlock> FinalizeBlock(std::shared_ptr<CBlock> pblock)
 {
+    LOCK(cs_main); // For LookupBlockIndex
+    GenerateCoinbaseCommitment(*pblock, LookupBlockIndex(pblock->hashPrevBlock), Params().GetConsensus());
+
     pblock->hashMerkleRoot = BlockMerkleRoot(*pblock);
 
     while (!CheckProofOfWork(pblock->GetHash(), pblock->nBits, Params().GetConsensus())) {
@@ -79,13 +98,13 @@ std::shared_ptr<CBlock> FinalizeBlock(std::shared_ptr<CBlock> pblock)
 }
 
 // construct a valid block
-const std::shared_ptr<const CBlock> GoodBlock(const uint256& prev_hash)
+std::shared_ptr<const CBlock> GoodBlock(const uint256& prev_hash)
 {
     return FinalizeBlock(Block(prev_hash));
 }
 
 // construct an invalid block (but with a valid header)
-const std::shared_ptr<const CBlock> BadBlock(const uint256& prev_hash)
+std::shared_ptr<const CBlock> BadBlock(const uint256& prev_hash)
 {
     auto pblock = Block(prev_hash);
 
@@ -185,4 +204,131 @@ BOOST_AUTO_TEST_CASE(processnewblock_signals_ordering)
     BOOST_CHECK_EQUAL(sub.m_expected_tip, ::ChainActive().Tip()->GetBlockHash());
 }
 
+/**
+ * Test that mempool updates happen atomically with reorgs.
+ *
+ * This prevents RPC clients, among others, from retrieving immediately-out-of-date mempool data
+ * during large reorgs.
+ *
+ * The test verifies this by creating a chain of `num_txs` blocks, matures their coinbases, and then
+ * submits txns spending from their coinbase to the mempool. A fork chain is then processed,
+ * invalidating the txns and evicting them from the mempool.
+ *
+ * We verify that the mempool updates atomically by polling it continuously
+ * from another thread during the reorg and checking that its size only changes
+ * once. The size changing exactly once indicates that the polling thread's
+ * view of the mempool is either consistent with the chain state before reorg,
+ * or consistent with the chain state after the reorg, and not just consistent
+ * with some intermediate state during the reorg.
+ */
+BOOST_AUTO_TEST_CASE(mempool_locks_reorg)
+{
+    bool ignored;
+    auto ProcessBlock = [&ignored](std::shared_ptr<const CBlock> block) -> bool {
+        return ProcessNewBlock(Params(), block, /* fForceProcessing */ true, /* fNewBlock */ &ignored);
+    };
+
+    // Process all mined blocks
+    BOOST_REQUIRE(ProcessBlock(std::make_shared<CBlock>(Params().GenesisBlock())));
+    auto last_mined = GoodBlock(Params().GenesisBlock().GetHash());
+    BOOST_REQUIRE(ProcessBlock(last_mined));
+
+    // Run the test multiple times
+    for (int test_runs = 3; test_runs > 0; --test_runs) {
+        BOOST_CHECK_EQUAL(last_mined->GetHash(), ::ChainActive().Tip()->GetBlockHash());
+
+        // Later on split from here
+        const uint256 split_hash{last_mined->hashPrevBlock};
+
+        // Create a bunch of transactions to spend the miner rewards of the
+        // most recent blocks
+        std::vector<CTransactionRef> txs;
+        for (int num_txs = 22; num_txs > 0; --num_txs) {
+            CMutableTransaction mtx;
+            mtx.vin.push_back(CTxIn{COutPoint{last_mined->vtx[0]->GetHash(), 1}, CScript{}});
+            mtx.vin[0].scriptWitness.stack.push_back(V_OP_TRUE);
+            mtx.vout.push_back(last_mined->vtx[0]->vout[1]);
+            mtx.vout[0].nValue -= 1000;
+            txs.push_back(MakeTransactionRef(mtx));
+
+            last_mined = GoodBlock(last_mined->GetHash());
+            BOOST_REQUIRE(ProcessBlock(last_mined));
+        }
+
+        // Mature the inputs of the txs
+        for (int j = COINBASE_MATURITY; j > 0; --j) {
+            last_mined = GoodBlock(last_mined->GetHash());
+            BOOST_REQUIRE(ProcessBlock(last_mined));
+        }
+
+        // Mine a reorg (and hold it back) before adding the txs to the mempool
+        const uint256 tip_init{last_mined->GetHash()};
+
+        std::vector<std::shared_ptr<const CBlock>> reorg;
+        last_mined = GoodBlock(split_hash);
+        reorg.push_back(last_mined);
+        for (size_t j = COINBASE_MATURITY + txs.size() + 1; j > 0; --j) {
+            last_mined = GoodBlock(last_mined->GetHash());
+            reorg.push_back(last_mined);
+        }
+
+        // Add the txs to the tx pool
+        {
+            LOCK(cs_main);
+            CValidationState state;
+            std::list<CTransactionRef> plTxnReplaced;
+            for (const auto& tx : txs) {
+                BOOST_REQUIRE(AcceptToMemoryPool(
+                    ::mempool,
+                    state,
+                    tx,
+                    /* pfMissingInputs */ &ignored,
+                    &plTxnReplaced,
+                    /* bypass_limits */ false,
+                    /* nAbsurdFee */ 0));
+            }
+        }
+
+        // Check that all txs are in the pool
+        {
+            LOCK(::mempool.cs);
+            BOOST_CHECK_EQUAL(::mempool.mapTx.size(), txs.size());
+        }
+
+        // Run a thread that simulates an RPC caller that is polling while
+        // validation is doing a reorg
+        std::thread rpc_thread{[&]() {
+            // This thread is checking that the mempool either contains all of
+            // the transactions invalidated by the reorg, or none of them, and
+            // not some intermediate amount.
+            while (true) {
+                LOCK(::mempool.cs);
+                if (::mempool.mapTx.size() == 0) {
+                    // We are done with the reorg
+                    break;
+                }
+                // Internally, we might be in the middle of the reorg, but
+                // externally the reorg to the most-proof-of-work chain should
+                // be atomic. So the caller assumes that the returned mempool
+                // is consistent. That is, it has all txs that were there
+                // before the reorg.
+                assert(::mempool.mapTx.size() == txs.size());
+                continue;
+            }
+            LOCK(cs_main);
+            // We are done with the reorg, so the tip must have changed
+            assert(tip_init != ::ChainActive().Tip()->GetBlockHash());
+        }};
+
+        // Submit the reorg in this thread to invalidate and remove the txs from the tx pool
+        for (const auto& b : reorg) {
+            ProcessBlock(b);
+        }
+        // Check that the reorg was eventually successful
+        BOOST_CHECK_EQUAL(last_mined->GetHash(), ::ChainActive().Tip()->GetBlockHash());
+
+        // We can join the other thread, which returns when the reorg was successful
+        rpc_thread.join();
+    }
+}
 BOOST_AUTO_TEST_SUITE_END()